Prayers Against Spiritual Causes of Sickness: Breaking Unseen Chains of Infirmity

 

You’ve prayed. You’ve stood on God’s word. You’ve believed for healing, yet the sickness persists, returning like a familiar, unwelcome shadow. The pain moves, the symptoms shift, and the doctors are perplexed. 

In these moments, the Holy Spirit whispers a crucial truth: not all sickness is merely physical. Some illnesses have spiritual roots, unseen chains that must be broken for lasting wholeness to manifest. 

Jesus did not just heal the sick; He confronted the spiritual forces behind the infirmities. When He healed the woman bent over for eighteen years, He declared, "So ought not this woman, being a daughter of Abraham, whom Satan has bound, think of it, for eighteen years, be loosed from this bond on the Sabbath?" (Luke 13:16). 

He identified Satan as the source of her bondage. Your persistent ailment may also be a bondage that requires not just prayer for healing, but a declaration of war against its spiritual cause.

Identifying and Confronting Spiritual Roots

Understanding the battlefield is half the victory. Sickness can be rooted in several spiritual grounds that must be addressed.

1. Generational Curses: Patterns of specific illnesses passed down family lines are often indicators of a curse that needs breaking (Exodus 20:5).
2. Personal Sin and Unforgiveness: Unconfessed sin and bitterness can open doors to physical affliction (James 5:16, John 5:14).
3. Word Curses: Negative, harmful words spoken over you, perhaps even in your childhood or by medical reports, can establish strongholds of infirmity.
4. Direct Spiritual Attack: Sometimes, sickness is a direct assignment from the enemy to hinder, discourage, or destroy a believer (Job 2:7, Acts 10:38).
5. Soul Ties: Unhealthy spiritual and emotional bonds with people can transfer spiritual and physical affliction.
   
   

This is spiritual surgery. It requires honesty before God and aggressive faith. Pray these points with determination. You are not just asking; you are severing, breaking, and dismantling. 

If you identify with any specific root, like unforgiveness or a generational pattern, linger on those points. This is a prayer of deliverance.

For the foundational truth that gives you the authority to pray these prayers, immerse yourself in our pillar article: By His Stripes: Praying with Authority for Healing and Divine Health.

Powerful Prayer Points Against Spiritual Causes of Sickness

Pray these points aggressively. Command every spiritual root of sickness to be exposed and destroyed.

Breaking Generational Curses of Sickness

1. Heavenly Father, I present myself before You and ask for the light of Your Spirit to reveal any generational curse of sickness operating in my life.
2. I apply the precious blood of Jesus Christ to break every curse of [name the specific sickness, e.g., diabetes, cancer, mental illness] from my father’s and mother’s bloodlines.
3. I renounce and revoke every covenant my ancestors made with idols, witch doctors, or false gods that opened the door to sickness in our lineage.
4. I decree that the generational curse is broken today by the superior blood of Jesus; its power over my health is forever destroyed.
5. I declare that I and my children are now under the blessing of Abraham and the covenant of health in Christ Jesus (Galatians 3:13-14).
   
   

Dealing with Personal Sin and Unforgiveness

6. Holy Spirit, search my heart; reveal any unconfessed sin, bitterness, or unforgiveness that has given ground to sickness in my body.
7. I confess the sin of [name any sin revealed] and I receive Your forgiveness and cleansing by the blood of Jesus (1 John 1:9).
8. I now choose from my heart to forgive [name the person(s)] for what they did to me. I release them, and I cut the tie between this unforgiveness and my sickness.
9. I close every door I opened to the enemy through sin, wrong relationships, or occult involvement. I reclaim this ground for the Kingdom of God.
10. I command every spirit of guilt, condemnation, and self-hatred that feeds on my past sins to leave me now in Jesus’ name.
    
    

Nullifying Word Curses and Negative Declarations

1. I break the power of every negative word, evil prophecy, or harmful declaration ever spoken over my health, whether by others, doctors, or myself.
2. I silence every voice of infirmity, death, and sickness that has been echoing in my mind. I choose to listen only to the report of the Lord.
3. I cancel every hex, jinx, spell, or witchcraft prayer sent to make me sick. I send it back to its source, nullified by the fire of the Holy Spirit.
4. I decree that my body is sanctified and healed by the Word of God; no weapon of words formed against my health shall prosper (Isaiah 54:17).
5. My mouth shall now only speak life, health, and strength over my body, according to the Word of God.

Rebuking Spirits of Infirmity and Affliction

16. I take authority over you, every spirit of infirmity, affliction, and sickness assigned against my body. I command you to loose your grip and get out now!
17. I rebuke and bind the strongman spirit behind this persistent sickness. I render you powerless and cast you out in the mighty name of Jesus.
18. I command every demonic plant of sickness the enemy has sown in my body to be uprooted, burned, and destroyed by the fire of God.
19. I break every satanic assignment of pain, inflammation, and malfunction. Your mission against my health is failed.
20. I loose God’s angels to war against and drive out every demonic spirit connected to this sickness from my life (Psalm 103:20).
    
    

Severing Ungodly Soul Ties

21. In the name of Jesus, I now sever every ungodly soul tie formed with [name person(s)] through sexual sin, unhealthy relationships, or covenants.
22. I break every transfer of sickness and spiritual defilement that came to me through these ungodly connections.
23. I command my soul, my mind, will, and emotions to be free from every unhealthy attachment and return to their proper alignment with God.
24. I ask the Holy Spirit to heal the wounds in my soul that made me vulnerable to these unhealthy ties.
25. I declare that I am now joined only to the Lord, and I am one spirit with Him (1 Corinthians 6:17).
    
    

Reclaiming Your Health and Freedom

26. Father, I thank You for my deliverance and freedom from every spiritual root of sickness. I receive my complete healing now.
27. I reclaim every part of my body that was held captive by spiritual forces. Every organ, every cell now functions in the freedom of Christ.
28. I put on the whole armor of God and stand against every attempt of the enemy to re-establish these spiritual roots in my life.
29. I declare that my body is a sanctified, healed, and delivered temple of the Holy Spirit, and no plague shall come near my dwelling (Psalm 91:10).
30. From this day forward, I walk in the liberty and wholeness that Christ has purchased for me. I am free indeed!
    
    

For prayers that focus on the physical manifestation of healing, explore our guide to Prayers for Divine Health and Supernatural Strength.

Walk in Your Deliverance

The chains are broken. The roots are severed. Do not continue to see yourself as the sick person bound by that familiar spirit. You are delivered. Walk in this new reality. When a symptom tries to return, remind it of its broken legal right. Command it to leave in the name of Jesus.

I challenge you to pray through these points thoroughly and consistently until you have the inner witness that every root has been dealt with.

This is a battle worth winning. Share this powerful resource with anyone you know who is in a similar struggle. Forward this link to them today.

Declare your freedom in the comments below. Write, "I am free from every spiritual root of sickness!" Your testimony will shatter the enemy's plans for others.

Stand firm in the liberty Christ has given you. You are healed, delivered, and made whole.

This article is part of our comprehensive healing series. For prayers in the face of severe diagnosis, see Prayers for Terminal Sickness and Chronic Illness. For prayers for inner wounds, see Prayers for Emotional Healing and Recovery from Trauma. To intercede for family, use Prayers for a Loved One's Health and Salvation. And for prayers for those in the medical field, see Prayers for Medical Professionals and Treatment Success.

For further study on spiritual warfare, ministries like Ellen G. White Estate provide resources that explore the Great Controversy theme and Christ's victory over evil.